Journals

Journal Name:   IRAETC Journal of Medical Science Sciences
Abbr. Title:   IRAETC J. Med. Sci.
ISSN(Print):   xxxx-xxxx
ISSN(Online):   xxxx-xxxx
Frequency:   Bi-Monthly
Language:   English
Chief Editor:   Dr. James Kay, PhD
Publisher:   IRAETC PUBLISHER
Country of Origin:   Bangladesh

Research Article

Preliminary Phytochemical and Lipoprotein Studies of Desmodium velutinum Aqueous Leaves Extract on Albino Wistar Rats

Eze-Steven, P. E and Ude, C. M

Cross Current Int J Med Biosci, 2019; 1(1):1-5.

10.36344/ccijmb.2019.v01i01.001

168 Downloads | 03-Dec-2022

ABSTRACT

Studies on phytochemical analyses and aqueous leaves extract of Desmodium velutinum was carried using albino Wistar rats. Twenty eight (28) albino wistar rats used for this study were randomly distributed into four groups (I to IV) of seven (7) rats each. Test animals in groups II, III, and IV were initially fed with a high fat diet (10mg/kg) for 12 days. Group II animals remained untreated. The groups III and IV animals were later treated with 5 mg/kg of atorvastatin and 5 mg/kg of D. velutinum, respectively for 4 days. However, the group I rats were fed with normal feed for 12 days and served as the control. The serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels were determined from blood samples of the various groups of rats. The result showed that there was a significant (p < 0.05) reduction in the serum TC, HDL-C, LDL-C, and TG concentrations of test animals following the administration of the atorvastatin and the extract. Alkaloids, tannins, flavonoids and reducing sugars were found to be highly present in the crude extract. Other phytochemicals present in the extract were saponins, carbohydrate, steroids, cyanide and terpenoid. These findings indicate that the use of the extract lowered the serum lipid profile of albino wistar rats and may be of clinical importance to individuals at risk of cardiovascular disease.

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10 Downloads | 10-Jan-2022

ABSTRACT

Bob Harvey first met Annette Adkins during study hall in 1955—and was immediately smitten. "I couldn’t take my eyes off her," Harvey told the New York Times. "She had auburn hair and a stunningly beautiful face and her eyes were just, wow." The two teens ended up going to prom together, but as many young relationships go, they lost touch after high school and married other people. Harvey never forgot about Adkins, though. In 2017, after his wife died, he searched for Adkins on Google and discovered she had also become widowed. He sent her a card with his phone number and after chatting for a bit, Harvey drove 500 miles to visit her, stopping only for gas and a bouquet of carnations. "I handed her the flowers, and then I cupped her face in my hand and said, 'Whether you like it or not, I’m going to kiss you,'" he recalled. In October, the high school sweethearts married at a '50s-style diner and danced to Johnny Mathis—just like they did at prom 63 years earlier.